'Safe' containers will never respawn their contents, retaining the contents that are deposited in them. You have to get some information from Troike about mysterious weapon supplies or get to know what Clanden is into. What happened to the Brotherhood of Steel? If you upgrade ED-E with stuff in his inventory, you will lose whatever is in there. I am playing Fallout New Vegas after finishing Fallout 3, and I am at 20 hours playtime. He leaves eventually and it's an open residence that I use until I get to Novac. This is because these containers are programmed to randomization the content it contains. Side with Cachino and help him to thwart the Family plans. Discussion in 'Fallout: New Vegas Discussion' started by Ceph, Mar 25, 2013. Because of that I suggest using a safe house to store your items, Keep one kind of item in each box.